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case study

Charlie, 8-year-old male castrated Labrador

“Early detection can make all the difference,
and in Charlie’s case, it truly did.⁠”
– Dr. Sue Cancer Vet

Charlie: case background

  • Presenting with 2-week history of uveitis and blindness
  • Work up and initial treatments started with internist
  • Confirmed intermediate to large cell B-cell lymphoma
  • Diagnosed via cytology of popliteal lymph nodes
  • Started CHOP 8 September 2024
  • Transferred to Oncology

Monthly rechecks

4 February 2025: 

  • Normal exam: CBC, chemistry panel and Nu.Q® Vet Cancer Test

11 March, 2025:

  • Owners requested CBC, chemistry panel and T4
  • Prominent popliteal LN, unable to get diagnostic sample to submit
  • Nu.Q® Vet Cancer Test: 557 ng/mL – high risk
  • Went in exam room to discuss with owner
  • Plan:
    • Thoracic radiographs: normal
    • Abdominal ultrasound

 

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Ultrasound results & next steps

    • Normal size
    • Within the tail of the spleen is a solitary, hypoechoic nodule, measuring 0.68×0.96 cm
    • Expanded population of large lymphocytes, consistent with recurrence of large cell lymphoma
    • With mild extramedullary hematopoiesis
    • Restarted chemo the following week
ultrasound
charlie spleen LSA OR
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