Sepsis

Our Nu.Q^® NETs assay detects diseases associated with NETosis, such as sepsis. It has the potential to help doctors accurately diagnose disease and could also help predict disease severity, measure treatment response and monitor disease progression.

This simple, low-cost, accessible test quantifies an individual’s level of circulating H3.1 nucleosomes in the blood stream, a surrogate marker for Neutrophil Extracellular Traps (NETs). Although NETs play a critical role in our normal immune response, elevated levels of NETs can lead to tissue damage, and in severe cases, sepsis, organ failure and death.

We are collaborating with centres of excellence worldwide to ensure Nu.Q^® NETs can be introduced effectively into clinical settings. It could be used to screen patients for sepsis when they present with symptoms in the emergency room, or if their condition deteriorates on a hospital ward.